Journal article

Reconstructing a transmission network and identifying risk factors of secondary transmissions in the 2010 foot-and-mouth disease outbreak in Japan

Yoko Hayama, Simon M Firestone, Mark A Stevenson, Takehisa Yamamoto, Tatsuya Nishi, Yumiko Shimizu, Toshiyuki Tsutsui

Transboundary and Emerging Diseases | WILEY | Published : 2019

Abstract

Research aimed at understanding transmission networks, representing a network of "who infected whom" for an infectious disease outbreak, have been actively conducted in recent years. Transmission network models incorporating epidemiological and genetic data are valuable for elucidating disease transmission pathways. In this study, we reconstructed the transmission network of the foot-and-mouth disease (FMD) epidemic in Japan in 2010, and explored farm-level risk factors associated with increased risk of secondary transmission. A published, systematic Bayesian transmission network model was applied to epidemiological data of 292 infected farms and whole genome sequence data of 104 of the infe..

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