Journal article

A novel method to assess pial collateralization from stroke perfusion MRI: subdividing T-max into anatomical compartments

Arne Potreck, Fatih Seker, Angelika Hoffmann, Johannes Pfaff, Simon Nagel, Martin Bendszus, Sabine Heiland, Mirko Pham



OBJECTIVES: To develop and validate a quantitative and observer-independent method to evaluate pial collateral circulation by DSC-perfusion MRI and test whether this novel method delivers diagnostic information which is redundant to or independent from conventional penumbra imaging by the mismatch approach. METHODS: We retrospectively identified 47 patients with M1 occlusion who underwent MR diffusion/perfusion imaging and mechanical thrombectomy at our facility. By automated registration and segmentation, Tmax delays were attributed specifically to the pial, cortical and parenchymal compartments. The resulting pial volumes at delay were defined as the pial Tmax map-assessed collateral score..

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University of Melbourne Researchers