Journal article

Simple Colorimetric Method for Quantification of Surface Carboxy Groups on Polymer Particles

Andreas Hennig, Angelika Hoffmann, Heike Borcherding, Thomas Thiele, Uwe Schedler, Ute Resch-Genger

ANALYTICAL CHEMISTRY | AMER CHEMICAL SOC | Published : 2011

Abstract

We present a novel, simple, and fast colorimetric method to quantify the total number of carboxy groups on polymer microparticle and nanoparticle surfaces. This method exploits that small divalent transition metal cations (M(2+) = Ni(2+), Co(2+), Cd(2+)) are efficiently bound to these surface functional groups, which allows their extraction by a single centrifugation step. Remaining M(2+) in the supernatant is subsequently quantified spectrophotometrically after addition of the metal ion indicator pyrocatechol violet, for which Ni(2+) was identified to be the most suitable transition metal cation. We demonstrate that the difference between added and detected M(2+) is nicely correlated to the..

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University of Melbourne Researchers

Grants

Awarded by Federal Ministry of Economics and Technology


Funding Acknowledgements

Financial support from the Federal Ministry of Economics and Technology (Grant Number BMWI VI A2-17/03) is gratefully acknowledged.