Journal article

CoQ(10) and Cognition a Review and Study Protocol for a 90-Day Randomized Controlled Trial Investigating the Cognitive Effects of Ubiquinol in the Healthy Elderly

Con Stough, Madeleine Nankivell, David A Camfield, Naomi L Perry, Andrew Pipingas, Helen Macpherson, Keith Wesnes, Ruchong Ou, David Hare, Judy de Haan, Geoffrey Head, Peter Lansjoen, Alena Langsjoen, Brendan Tan, Matthew P Pase, Rebecca King, Renee Rowsell, Oliver Zwalf, Yossi Rathner, Matthew Cooke Show all

FRONTIERS IN AGING NEUROSCIENCE | FRONTIERS MEDIA SA | Published : 2019

Abstract

Introduction: With an aging population there is an important need for the development of effective treatments for the amelioration of cognitive decline. Multiple mechanisms underlie age-related cognitive decline including cerebrovascular disease, oxidative stress, reduced antioxidant capacity and mitochondrial dysfunction. CoQ10 is a novel treatment which has the potential to improve brain function in healthy elderly populations due to established beneficial effects on mitochondrial function, vascular function and oxidative stress. Methods and Analysis: We describe the protocol for a 90-day randomized controlled trial which examines the efficacy of Ubiquinol (200 mg/day) vs. placebo for the ..

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