Journal article
International, multicentre, observational study of fluid bolus therapy in neonates
Amy K Keir, Oliver Karam, Nicolette Hodyl, Michael J Stark, Helen G Liley, Prakesh S Shah, Simon J Stanworth, Scott Morris, Kathryn Browning Carmo, Koert De Waal, Michelle Stubbs, Helen Liley, Angela Pearson, Holly Campbell, Rodney W Hunt, Elizabeth Perkins, Sanoj KM Ali, Jennifer Bowen, Claire Jacobs, Mary Paradisis Show all
JOURNAL OF PAEDIATRICS AND CHILD HEALTH | WILEY | Published : 2019
DOI: 10.1111/jpc.14260
Abstract
AIM: To assess the prevalence, types and indications for fluid bolus therapy in neonates with haemodynamic compromise. METHODS: This was a pragmatic, international, multicentre observational study in neonatal units across Australasia, Europe and North America with a predefined study period of 10-15 study days per participating neonatal unit between December 2015 and March 2017. Infants ≤28 days of age who received a fluid bolus for the management of haemodynamic compromise (≥10 mL/kg given at ≤6 h) were included. RESULTS: A total of 163 neonates received a bolus over 8479 eligible patient days in 41 neonatal units. Prevalence of fluid bolus therapy varied between centres from 0 to 28.6% of a..
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Funding Acknowledgements
AK Keir received support through an Australian Government Research Training Program Scholarship and through the Eric Burnard Fellowship from the Royal Australasian College of Physicians Foundation for this work. The Women's and Children's Hospital Foundation and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC) provided financial support for this study. [Correction added on 1 April 2019, after first online publication: The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC) was added to the "Acknowledgements" seciton.]