EVAULATION OF INTRA-ARTICULAR ADIPOSE DERIVED MESENCHYMAL STEM CELL THERAPY IN THE TREATMENT OF SYMPTOMATIC KNEE OSTEOARTHRITIS - A RANDOMISED CONTROLLED TRIAL.

Abstract

Background & Aim Background Osteoarthritis is a degenerative condition and a leading cause of pain and disability world wide. Current medical treatments are aimed at symptomatic control and do not achieve disease modification. Surgical interventions including total joint arthroplasty can be unpredictable. Pre-clinical and early clinical trials have shown initial evidence of safety and efficacy of mesenchymal stem cell (MSC) therapies. Aim To evaluate the efficacy of autologous adipose derived mesenchymal stem cell (AdMSC) therapy on pain, function and disease modification in symptomatic knee osteoarthritis (OA). Methods, Results & Conclusion Methods 30 participants with symptomatic knee oste..