The association between gestational diabetes mellitus, antipsychotics and severe mental illness in pregnancy: A multicentre study

Abstract

BACKGROUND: There have been conflicting findings for severe mental illnesses and the risk for gestational diabetes mellitus (GDM). Outside of pregnancy, both severe mental illnesses and specific antipsychotic medications have been associated with an elevated risk for metabolic disorders, including type 2 diabetes mellitus. AIM: This study examined the risk of developing GDM in relation to mental disorder, psychotropic treatment and comorbid risk factors. MATERIALS AND METHODS: A retrospective study of 539 pregnant women with mental disorders was carried out. Measures included GDM diagnosis, mental health diagnosis, psychotropic medication, body mass index, age, smoking, alcohol and illicit s..