Obesity in older adults: Effect of degree of weight loss on cardiovascular markers and medications

CJ Haywood; LA Prendergast; R Lim; M Lappas; WK Lim; J Proietto

Journal article

Obesity in older adults: Effect of degree of weight loss on cardiovascular markers and medications

CJ Haywood, LA Prendergast, R Lim, M Lappas, WK Lim, J Proietto

Clinical Obesity | WILEY | Published : 2019

DOI: 10.1111/cob.12316

Download PDF

Abstract

Obesity worsens the age-related tendency towards cardiovascular disease and diabetes. Older adults are vulnerable to medication adverse effects. Intentional weight loss in older adults with obesity has been shown to improve cardiovascular and glycaemic markers. The effect of rapid weight loss induced by very-low-calorie diets (VLCDs) on these markers has not been evaluated in this group. In this 12-week study, participants were randomized to one of healthy eating, hypocaloric diet or VLCD, all combined with three times weekly exercise (Ex/HE, Ex/Diet, Ex/VLCD, respectively). The effects of these interventions on weight, blood pressure, lipids, glucose and HbA1c, inflammatory markers and card..

View full abstract

University of Melbourne Researchers

Cilla Haywood Author

Martha Lappas Author

Wen Kwang Lim Author

Joseph Proietto Author

Related Projects (2)

OBESITY IN THE ELDERLY

The population is ageing and the prevalence of obesity is increasing. The “Baby Boomer” generation has the highest prevalence of obesity of ..

Obesity in the Elderly: impact of weight loss therapy on physiology and function.

The aim of this study is to assess the safety, tolerability, weight-loss efficacy, change in lean body mass and impact of cognition of three..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

National Health and Medical Research Council, Grant/Award Number: APP1044334; National Health and Medical Research Council Medical/Dental Postgraduate Scholarship, Grant/Award Number: APP1056512