Journal article

Obesity in older adults: Effect of degree of weight loss on cardiovascular markers and medications

Cilla J Haywood, Luke A Prendergast, Ratana Lim, Martha Lappas, Wen Kwang Lim, Joseph Proietto

CLINICAL OBESITY | WILEY | Published : 2019

Abstract

Obesity worsens the age-related tendency towards cardiovascular disease and diabetes. Older adults are vulnerable to medication adverse effects. Intentional weight loss in older adults with obesity has been shown to improve cardiovascular and glycaemic markers. The effect of rapid weight loss induced by very-low-calorie diets (VLCDs) on these markers has not been evaluated in this group. In this 12-week study, participants were randomized to one of healthy eating, hypocaloric diet or VLCD, all combined with three times weekly exercise (Ex/HE, Ex/Diet, Ex/VLCD, respectively). The effects of these interventions on weight, blood pressure, lipids, glucose and HbA1c , inflammatory markers and car..

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Grants

Awarded by National Health and Medical Research Council


Awarded by National Health and Medical Research Council Medical/Dental Postgraduate Scholarship


Funding Acknowledgements

National Health and Medical Research Council, Grant/Award Number: APP1044334; National Health and Medical Research Council Medical/Dental Postgraduate Scholarship, Grant/Award Number: APP1056512