Journal article

International multicentre retrospective cohort study of ocular adnexal marginal zone B-cell lymphoma

Tine Gadegaard Hindso, Bita Esmaeli, Frederik Holm, Lauge Hjorth Mikkelsen, Peter Kristian Rasmussen, Sarah E Coupland, Paul T Finger, Gerardo F Graue, Hans E Grossniklaus, Santosh G Honavar, Jwu Jin Khong, Penelope A McKelvie, Kaustubh Mulay, Lene Dissing Sjo, Geeta K Vemuganti, Bradley A Thuro, Steffen Heegaard

British Journal of Ophthalmology | BMJ PUBLISHING GROUP | Published : 2020


BACKGROUNDS/AIMS: To date, this is the largest cohort study on extranodal marginal zone B-cell lymphoma (EMZL) of the ocular adnexa (OA). The aim of the study was to characterise the clinical features of OA-EMZL. METHODS: A retrospective multicentre study involving seven international eye cancer centres. Data were collected from 1 January 1980 through 31 December 2017. A total of 689 patients with OA-EMZL were included. RESULTS: The median follow-up time was 42 months. The median age was 62 years (range, 8-100 years), and 55 % (378/689 patients) of patients were women. The majority of patients (82%, 558/680 patients) were diagnosed with primary OA-EMZL with Ann Arbor stage IE (90%, 485/541 p..

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University of Melbourne Researchers


Funding Acknowledgements

This study was supported by grants from Synoptik-Fonden, Copenhagen, Denmark, and Fight for Sight Denmark, Copenhagen, Denmark. MD Lauge Hjorth Mikkelsen was supported by The Candy Foundation.