Journal article

Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery

D Christiansen, L Earnest-Silveira, B Grubor-Bauk, DK Wijesundara, I Boo, PA Ramsland, E Vincan, HE Drummer, EJ Gowans, J Torresi

Scientific Reports | NATURE PUBLISHING GROUP | Published : 2019

DOI: 10.1038/s41598-019-45461-z

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Related Projects (2)

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HEPATITIS C VACCINE

Hepatitis C virus is responsible for over 300,000 deaths per year world wide and in Australia causes 10,000 new cases each year. A vaccine t..

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DEVELOPING A QUADRIVALENT HCV VACCINE

A vaccine for hepatitis C virus (HCV) is not yet available. Immune responses that are able to protect against infection are possible, making..

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Awarded by National Health and Medical Research Council (NHMRC) of Australia

Awarded by NHMRC Practitioner Fellowship

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC) of Australia, grant numbers 1060436 and 1126379. JT was supported by an NHMRC Practitioner Fellowship, number 106043.

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Keywords

Hepatitis C Antibodies
Broadly Neutralizing Antibodies
Antiviral Treatment
Multidisciplinary Sciences
Immunization
Drug Delivery Systems
Hepatitis C
Viral Envelope Proteins
Animals
T-Cell Responses
Hepacivirus
Glycoprotein
Human Monoclonal-Antibodies
Immune-Responses
Virus-Like Particles
Vaccination
Inject Drugs
Science & Technology
Viral Hepatitis Vaccines
Science & Technology - Other Topics
Drug Evaluation, Preclinical
Swine
Hepatitis-C Infection
Antibodies, Neutralizing