Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study.

J Bartoszko; KE Thorpe; A Laupacis; DN Wijeysundera; METS Study Investigators; International and National Coordinators; Central Project Office Operations Committee; CPET Methods Committee; Outcome Adjudication Committee; International Steering Committee

Journal article

Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study.

J Bartoszko, KE Thorpe, A Laupacis, DN Wijeysundera, undefined METS Study Investigators, undefined International and National Coordinators, undefined Central Project Office Operations Committee, undefined CPET Methods Committee, undefined Outcome Adjudication Committee, undefined International Steering Committee

British Journal of Anaesthesia | Published : 2019

DOI: 10.1016/j.bja.2019.04.058

Abstract

BACKGROUND: Preoperative anaemia is associated with elevated risks of postoperative complications. This association may be explained by confounding related to poor cardiopulmonary fitness. We conducted a pre-specified substudy of the Measurement of Exercise Tolerance before Surgery (METS) study to examine the associations of preoperative haemoglobin concentration with preoperative cardiopulmonary exercise testing performance (peak oxygen consumption, anaerobic threshold) and postoperative complications. METHODS: The substudy included a nested cross-sectional analysis and nested cohort analysis. In the cross-sectional study (1279 participants), multivariate linear regression modelling was use..

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