Journal article

Chronic Cough and Gastroesophageal Reflux in Children CHEST Guideline and Expert Panel Report

Anne B Chang, John J Oppenheimer, Peter J Kahrilas, Ahmad Kantar, Bruce K Rubin, Miles Weinberger, Richard S Irwin, Todd M Adams, Kenneth W Altman, Elie Azoulay, Alan F Barker, Donald C Bolser, Surinder S Birring, Sidney S Braman, Christopher Brightling, Priscilla Callahan-Lyon, Anne B Chang, Terrie Cowley, Paul Davenport, Ali A El Solh Show all

CHEST | ELSEVIER SCIENCE BV | Published : 2019

Abstract

BACKGROUND: Whether gastroesophageal reflux (GER) or GER disease (GERD) causes chronic cough in children is controversial. Using the Population, Intervention, Comparison, Outcome (PICO) format, we undertook four systematic reviews. For children with chronic cough (> 4-weeks duration) and without underlying lung disease: (1) who do not have gastrointestinal GER symptoms, should empirical treatment for GERD be used? (2) with gastrointestinal GER symptoms, does treatment for GERD resolve the cough? (3) with or without gastrointestinal GER symptoms, what GER-based therapies should be used and for how long? (4) if GERD is suspected as the cause, what investigations and diagnostic criteria best de..

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University of Melbourne Researchers