Journal article

Time to tweak the TTO: results from a comparison of alternative specifications of the TTO.

Matthijs M Versteegh, Arthur E Attema, Mark Oppe, Nancy J Devlin, Elly A Stolk

European Journal of Health Economics | Published : 2013


This article examines the effect that different specifications of the time trade-off (TTO) valuation task may have on values for EQ-5D-5L health states. The new variants of the TTO, namely lead-time TTO and lag-time TTO, along with the classic approach to TTO were compared using two durations for the health states (15 and 20 years). The study tested whether these methods yield comparable health-state values. TTO tasks were administered online. It was found that lag-time TTO produced lower values than lead-time TTO and that the difference was larger in the longer time frame. Classic TTO values most resembled those of the lag-time TTO in a 20-year time frame in terms of mean absolute differenc..

View full abstract