Journal article

Lung function: population epidemiology and concordance in Australian children aged 11-12 years and their parents

Liam Welsh, Gayan Kathriachchige, Tahmeed Raheem, Anneke C Grobler, Melissa Wake, Sarath Ranganathan

BMJ Open | BMJ PUBLISHING GROUP | Published : 2019


OBJECTIVES: To describe the epidemiology of lung function in Australian children aged 11-12 years and their parents, and explore the degree of intergenerational concordance. DESIGN: Cross-sectional study (the Child Health CheckPoint) nested in the Longitudinal Study of Australian Children (LSAC). SETTING: Assessment centres in seven Australian cities and eight regional towns, February 2015 to March 2016. Families unable to attend a clinic appointment were offered a home visit during the same period. PARTICIPANTS: 1874 families (53% of all eligible) participated in the study. Lung function data were available for 1759 children aged 11-12 years and 1774 parents (1668 biological pairs). OUTCOME..

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Awarded by National Health and Medical Research Council (NHMRC) of Australia

Awarded by Royal Children's Hospital Foundation

Awarded by Financial Markets Foundation for Children

Awarded by NHMRC Senior Research Fellowship

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC) of Australia (Project Grants 1041352, 1109355), The Royal Children's Hospital Foundation (2014-241), the Murdoch Children's Research Institute (MCRI), The University of Melbourne, the Financial Markets Foundation for Children (2014-055, 2016-310) and the National Centre for Longitudinal Data (NCLD). MW was supported by an NHMRC Senior Research Fellowship (1046518). The MCRI administered the research grants for the study and provided infrastructural support (IT and biospecimen management) to its staff and the study, but played no role in the conduct or analysis of the trial. DSS played a role in study design; however, no other funding bodies had a role in the study design and conduct; data collection, management, analysis and interpretation; preparation, review or approval of the manuscript; and decision to submit the manuscript for publication. Research at the MCRI is supported by the Victorian Government's Operational Infrastructure Support Program.