Journal article

Diagnostic Value of Mid-Thigh and Mid-Calf Bone, Muscle, and Fat Mass in Osteosarcopenia: A Pilot Study

Ebrahim Bani Hassan, Steven Phu, Sara Vogrin, Genesis Escobedo Terrones, Xaviera Perez, Isabel Rodriguez-Sanchez, Gustavo Duque

Calcified Tissue International | SPRINGER | Published : 2019


Osteosarcopenia is defined as the concomitant occurrence of osteoporosis and sarcopenia. Current lack of consensus on sarcopenia definitions, combined with the low sensitivity and specificity of screening methodologies, has resulted in varying prevalences of sarcopenia, and consequently osteosarcopenia diagnosis. Previous research indicates that mid-thigh is a potential surrogate region for the assessment of bone, muscle, and fat mass in a single, efficient and low-radiation dual x-ray absorptiometry (DXA) scan. We hypothesized that muscle and bone mass measurements in the mid-thigh region can be used to evaluate bone and muscle health and function. A retrospective study was conducted on com..

View full abstract


Funding Acknowledgements

This study was supported by the Australian Institute for Musculoskeletal Science (AIMSS) as the host institute. The authors would like to thank Mrs Solange Bernardo (the fracture liaison nurse) for coordinating the patient attendance and assistance in data collection. We are also grateful to Mrs Paula Casas for kindly reviewing the manuscript. Ebrahim Bani Hassan was supported by the Australian Medical Research Future Fund (MRFF) under MACH-RART Scheme.