Journal article

Assessment of the utility of a commercial calprotectin and lactoferrin rapid test in diagnosis of marmoset wasting syndrome

Anna Meredith, Guillaume Douay, Rina Maguire, Francis Cabana, Mélanie Bethet, Zi Teng Lim

JZAR, Journal of Zoo and Aquarium Research | European Association of Zoos and Aquaria | Published : 2019

Abstract

This study assessed the detection of faecal biomarkers in captive callitrichids affected by Marmoset Wasting Syndrome (MWS), using a commercial colored chromatographic immunoassay intended for the detection of calprotectin and lactoferrin in humans affected by inflammatory intestinal diseases. The test was applied to faecal samples from 77 animals of 11 callitrichid species. Animals were divided into two groups consisting of 23 animals affected by MWS and 54 apparently healthy animals. All samples tested negative for lactoferrin while 64.9 % tested positive for calprotectin. The commercial test exhibited a high sensitivity (95.6%) but a low specificity (48.1%) for calprotectin, indicating po..

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University of Melbourne Researchers