Journal article

Invasive fungal infections in children with acute lymphoblastic leukaemia: Results from four Australian centres, 2003-2013

SS Wang, RS Kotecha, A Bernard, CC Blyth, BJ McMullan, MP Cann, DK Yeoh, AW Bartlett, AL Ryan, AS Moore, PA Bryant, J Clark, GM Haeusler

Pediatric Blood and Cancer | WILEY | Published : 2019

Abstract

Background: Invasive fungal infections (IFI) are an important complication of acute lymphoblastic leukaemia (ALL) treatment. Our study describes the prevalence and outcomes of IFI in children with ALL. Methods: IFI episodes in children with primary or relapsed ALL, identified for The Epidemiology and Risk Factors for Invasive Fungal Infections in Immunocompromised Children study, were analysed. IFI were classified according to European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group criteria with a ‘modified-possible’ category included. Results: A total of 123 IFI episodes in 119 patients with ALL were included. A proven, probable, possible and ..

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