Journal article

Spontaneous and induced platelet aggregation in apparently healthy subjects in relation to age.

A Kuhnla, M Reinthaler, S Braune, A Maier, Gerhard Pindur, A Lendlein, F Jung

Clin Hemorheol Microcirc | Published : 2019

Abstract

Thrombotic disorders remain the leading cause of mortality and morbidity, despite the fact that anti-platelet therapies and vascular implants are successfully used today. As life expectancy is increasing in western societies, the specific knowledge about processes leading to thrombosis in elderly is essential for an adequate therapeutic management of platelet dysfunction and for tailoring blood contacting implants. This study addresses the limited available data on platelet function in apparently healthy subjects in relation to age, particularly in view of subjects of old age (80-98 years). Apparently healthy subjects between 20 and 98 years were included in this study. Platelet function was..

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