Journal article

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

You Li, Rachel M Reeves, Xin Wang, Quique Bassat, W Abdullah Brooks, Cheryl Cohen, David P Moore, Marta Nunes, Barbara Rath, Harry Campbell, Harish Nair, Sozinho Acacio, Wladimir J Alonso, Martin Antonio, Guadalupe Ayora Talavera, Darmaa Badarch, Vicky L Baillie, Gisela Barrera-Badillo, Godfrey Bigogo, Shobha Broor Show all



BACKGROUND: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (<5 years) and older people (≥65 years). A global report of the monthly activity of these viruses is needed to inform public health strategies and programmes for their control. METHODS: In this systematic analysis, we compiled data from a systematic literature review of studies published between Jan 1, 2000, and Dec 31, 2017; online datasets; and unpublished research data. Studies were eligible for inclusion if they reported laboratory-confirmed incidence data of human infection of influenza virus, ..

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Awarded by Innovative Medicines Initiative 2 Joint Undertaking

Awarded by Wellcome Trust

Awarded by CDC

Funding Acknowledgements

This study was supported by Respiratory Syncytial Virus Consortium in Europe (RESCEU). RESCEU has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No. 116019. This Joint Undertaking receives support from the EU's Horizon 2020 research and innovation programme and European Federation of Pharmaceutical Industries and Associations. YL and XW are supported by scholarships from China Scholarship Council. We thank Meagan E Peterson for her assistance in preparing the data collection template for collating data from RSV GEN investigators. We thank Alma Nurkic and the participating three labs in New South Wales, Australia for providing their data. We thank Andrea Gutierrez, Imane Jroundi, and Histoshi Oshitani for providing their local seasonality data. Funding for data collection in Kilifi, Kenya was from the Wellcome Trust (Grant ref#102975). Data from one study in Peru were contributed by employees of the US Government and were prepared as part of their official duties. Title 17 U.S.C. 105 provides that "Copyright protection under this title is not available for any work of the United States Government." Title 17 U.S.C. 101 defines a US Government work as a work prepared by a military service member or employee of the US Government as part of that person's official duties. The views expressed in this Article are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, nor the US Government. The study was supported by funded by work unit number DHP 67.7., GEIS-Lima 847705 82000 25GB B0016, CDC. The study protocol was approved by the Naval Medical Research Unit Number Six Institutional Review Board in compliance with all applicable Federal regulations governing the protection of human participants. Philippe Buchy is an employee of GlaxoSmithKline Vaccines. Bradford D Gessner is an employee of Pfizer Vaccines. Daniel E Noyola has participated as member of the speakers' bureau of AbbVie and Sanofi-Pasteur.