Journal article

Influenza in Children With Special Risk Medical Conditions A Systematic Review and Meta-analysis

Jane Tuckerman, Siobhan Misan, Nigel W Crawford, Helen S Marshall

PEDIATRIC INFECTIOUS DISEASE JOURNAL | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019

Abstract

BACKGROUND: Children with special risk medical conditions (SRMC) are over-represented in influenza hospitalizations. A systematic review was undertaken to determine whether children with SRMCs experience greater complications or severity following influenza infection. METHODS: Bibliographies of pertinent articles were searched in MEDLINE and EMBASE (1990 to March 2018) and contact made with the investigators of unpublished studies containing relevant data. Studies of children (aged ≤18 years) with a SRMC hospitalized with influenza were included. Outcomes were pneumonia, intensive care unit (ICU) admission, mechanical ventilation, neurologic outcomes (seizures, encephalopathy), death and len..

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Grants

Awarded by NHMRC Fellowship


Funding Acknowledgements

The authors have no financial relationships relevant to this article to disclose. No funding was secured for this study. This review was initiated as part of studies toward a Doctor of Philosophy (PhD) undertaken by Ms Tuckerman; funded by an Australian Government Research Training Program Scholarship (formally Australian Postgraduate Award). Prof Marshall is supported by NHMRC Fellowship APP1084951. This review is not sponsored or financed by a third party.