How well do the FRAX (Australia) and Garvan calculators predict incident fractures? Data from the Geelong Osteoporosis Study
KL Holloway-Kew, Y Zhang, AG Betson, KB Anderson, D Hans, K Hyde, GC Nicholson, NA Pocock, MA Kotowicz, JA Pasco
Osteoporosis International | SPRINGER LONDON LTD | Published : 2019
This study reports that both FRAX and Garvan calculators underestimated fractures in Australian men and women, particularly in those with osteopenia or osteoporosis. Major osteoporotic fractures were poorly predicted, while both calculators performed acceptably well for hip fractures. INTRODUCTION: This study assessed the ability of the FRAX (Australia) and Garvan calculators to predict fractures in Australian women and men. METHODS: Women (n = 809) and men (n = 821) aged 50-90 years, enrolled in the Geelong Osteoporosis Study, were included. Fracture risk was estimated using FRAX and Garvan calculators with and without femoral neck bone mineral density (BMD) (FRAXBMD, FRAXnoBMD, GarvanBMD, ..View full abstract
Awarded by National Health and Medical Research Council (NHMRC) of Australia
This study is supported by the National Health and Medical Research Council (NHMRC) of Australia (251638, 299831, 628582), the Geelong Regional Medical Foundation, Arthritis Foundation of Australia, and Perpetual Trustees.