Systematic endobronchial ultrasound-guided transbronchial needle aspiration improves radiotherapy planning in non-small cell lung cancer
Aidan Joseph Cole, Nicholas Hardcastle, Guy-Anne Turgeon, Roshini Thomas, Louis B Irving, Barton R Jennings, David Ball, Tomas Kron, Daniel P Steinfort, Shankar Siva
ERJ Open Research | European Respiratory Society | Published : 2019
Objectives: Patients suitable for radical chemoradiotherapy for lung cancer routinely have radiotherapy (planning) volumes based on positron emission tomography (PET)-computed tomography (CT) imaging alone. Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) can identify PET-occult malignancy and benign PET-avid regions. We investigated the impact of EBUS-TBNA on curative-intent radiotherapy in non-small cell lung cancer (NSCLC). Methods: A prospective multicentre trial was undertaken, investigating the impact of systematic EBUS-TBNA in addition to PET-CT for patients considered for radical chemoradiotherapy with NSCLC. A subset analysis of patients with discordant..View full abstract
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Awarded by National Health and Medical Research Council (Australia)
Funding was received from the National Health and Medical Research Council (Australia), grant numbers APP1122347 and GNT1121880. Funding information for this article has been deposited with the Crossref Funder Registry.