Conference Proceedings
IMMUNE-RELATED ADVERSE EVENTS INDUCED BY CANCER IMMUNOTHERAPIES. BIG DATA ANALYSIS OF 13,051 CASES (IMMUNOCANCER INTERNATIONAL REGISTRY)
Manuel Ramos-Casals, Oliver Lambotte, Marie Kostine, Leonard Calabrese, Maria Suarez-Almazor, Clifton Bingham, Timothy R Radstake, Chiara Baldini, Thierry Schaeverbeke, Jacques-Eric Gottenberg, Hendrik Schulze-Koops, Jan Leipe, Cassandra Calabrese, Pilar Brito-Zeron, Alejandra Flores-Chavez, Belchin Kostov, Soledad Retamozo, Gustavo Citera, Eva Aguilar, Michael Richter Show all
ANNALS OF THE RHEUMATIC DISEASES | BMJ PUBLISHING GROUP | Published : 2019
Abstract
Background The ImmunoCancer International Registry (ICIR) is a Big Data-Sharing multidisciplinary network composed by 39 specialists in Rheumatology, Internal Medicine, Immunology and Oncology from 18 countries focused on immune-related adverse events (irAEs) related to cancer immunotherapies (CIs). Objectives To analyse the worldwide scenario of irAEs associated with the use of CIs in this Century. Methods The first objective of the ICIR has been the development of a systematic literature review crossing CIs terms with immune diseases defined according to MedDRAVR 15.0. Results The cumulated number of cases per year of irAEs has increased exponentially, with 12,648 patients who developed 13..
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