Journal article

The effect of sex and body weight on lung volumes during sleep

Joanne Avraam, Andrew Dawson, Peter D Rochford, Danny J Brazzale, Fergal J O'Donoghue, John Trinder, Amy S Jordan

Sleep | OXFORD UNIV PRESS INC | Published : 2019

Abstract

STUDY OBJECTIVES: Low lung volumes are thought to contribute to obstructive sleep apnea (OSA). OSA is worse in the supine versus lateral body position, men versus women, obese versus normal-weight (NW) individuals and REM versus NREM sleep. All of these conditions may be associated with low lung volumes. The aim was to measure FRC during wake, NREM, and REM in NW and overweight (OW) men and women while in the supine and lateral body positions. METHODS: Eighty-one healthy adults were instrumented for polysomnography, but with nasal pressure replaced with a sealed, non-vented mask connected to an N2 washout system. During wakefulness and sleep, repeated measurements of FRC were made in both su..

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Grants

Awarded by National Health and Medical Research Council Australia


Awarded by Australian Research Council Future Fellowship


Funding Acknowledgements

This study was supported by grants from the National Health and Medical Research Council Australia (APP1025725) and Melbourne Research Grant Scheme (University of Melbourne). A.S.J. was supported by an Australian Research Council Future Fellowship (FT100100203).