Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis

A Cassini; LD Högberg; D Plachouras; A Quattrocchi; A Hoxha; GS Simonsen; M Colomb-Cotinat; ME Kretzschmar; B Devleesschauwer; M Cecchini; DA Ouakrim; TC Oliveira; MJ Struelens; C Suetens; DL Monnet; R Strauss; K Mertens; T Struyf; B Catry; K Latour; IN Ivanov; EG Dobreva; A Tambic Andraševic; S Soprek; A Budimir; N Paphitou; H Žemlicková; S Schytte Olsen; U Wolff Sönksen; P Märtin; M Ivanova; O Lyytikäinen; J Jalava; B Coignard; T Eckmanns; M Abu Sin; S Haller; GL Daikos; A Gikas; S Tsiodras; F Kontopidou; Á Tóth; Á Hajdu; Ó Guólaugsson; KG Kristinsson; S Murchan; K Burns; P Pezzotti; C Gagliotti; U Dumpis; A Liuimiene; M Perrin; MA Borg; SC de Greeff; JC Monen; MB Koek; P Elstrøm; D Zabicka; A Deptula; W Hryniewicz; M Caniça; PJ Nogueira; PA Fernandes; V Manageiro; GA Popescu; RI Serban; E Schréterová; S Litvová; M Štefkovicová; J Kolman; I Klavs; A Korošec; B Aracil; A Asensio; M Pérez-Vázquez; H Billström; S Larsson; JS Reilly; A Johnson; S Hopkins

Journal article

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis

A Cassini, LD Högberg, D Plachouras, A Quattrocchi, A Hoxha, GS Simonsen, M Colomb-Cotinat, ME Kretzschmar, B Devleesschauwer, M Cecchini, DA Ouakrim, TC Oliveira, MJ Struelens, C Suetens, DL Monnet, R Strauss, K Mertens, T Struyf, B Catry, K Latour Show all

Lancet Infectious Diseases | ELSEVIER SCI LTD | Published : 2019

DOI: 10.1016/S1473-3099(18)30605-4

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Abstract

Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed to estimate the burden of infections caused by antibiotic-resistant bacteria of public health concern in countries of the EU and European Economic Area (EEA) in 2015, measured in number of cases, attributable deaths, and disability-adjusted life-years (DALYs). Methods: We estimated the incidence of infections with 16 antibiotic resistance–bacterium combinations from European Antimicrobial Resistance Surveillance Network (EARS-Net) 2015 data that was country-corrected for population coverage. We ..

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