Journal article

The effect of smell and taste of milk during tube feeding of preterm infants (the Taste trial): a protocol for a randomised controlled trial

Friederike Beker, Judith Macey, Helen Liley, Ian Hughes, Peter G Davis, Emily Twitchell, Susan Jacobs

BMJ Open | BMJ PUBLISHING GROUP | Published : 2019


INTRODUCTION: Smell and taste of milk are not generally considered when tube feeding preterm infants. Preterm infants have rapid growth, particularly of the brain, and high caloric needs. Enteral feeding is often poorly tolerated which may lead to growth failure and long-term neurodevelopmental impairment. Smell and taste are strong stimulators of digestion and metabolism. We hypothesise that regular smell and taste during tube feeding will improve weight z-scores of very preterm infants at discharge from hospital. METHODS AND ANALYSIS: Taste is a randomised, unblinded two-centre trial. Infants born at <29 weeks' gestation and/or <1250 g at birth and admitted to a participating neonatal inte..

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Awarded by National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

The primary trial sponsor is Mater Misericordiae, contact: CEO Mater Research, Governance Office, email:, phone: +61 7 3163 3769. This work is supported by Mater Research Institute, the Department of Newborn Research at the RWH and the National Health and Medical Research Council (NHMRC) Program Grant (#1113902). PGD is supported by an NHMRC Practitioner Fellowship. The Royal Australasian College of Physicians and Paediatricians - Queensland Branch provides funding for statistical support.