Journal article
Early mobilization and quality of life after stroke Findings from AVERT
Toby B Cumming, Leonid Churilov, Janice Collier, Geoffrey Donnan, Fiona Ellery, Helen Dewey, Peter Langhorne, Richard Lindley, Marj Moodie, Amanda G Thrift, Julie Bernhardt, E Hibbert, R Melling, S Petrolo, T Purvis, H Williamson, P Adams, L Augoustakis, S Batcheler, S Berney Show all
Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019
Abstract
OBJECTIVE: To determine whether early and more frequent mobilization after stroke affects health-related quality of life. METHODS: A Very Early Rehabilitation Trial (AVERT) was an international, multicenter (56 sites), phase 3 randomized controlled trial, spanning 2006-2015. People were included if they were aged ≥18 years, presented within 24 hours of a first or recurrent stroke (ischemic or hemorrhagic), and satisfied preordained physiologic criteria. Participants were randomized to usual care alone or very early and more frequent mobilization in addition to usual care. Quality of life at 12 months was a prespecified secondary outcome, evaluated using the Assessment of Quality of Life 4D (..
View full abstractGrants
Awarded by National Health and Medical Research Council (NHMRC) of Australia
Awarded by Chest Heart and Stroke Scotland
Awarded by Northern Ireland Chest Heart and Stroke, Singapore Health
Awarded by UK Stroke Association
Awarded by UK National Institute of Health Research
Awarded by NHMRC
Awarded by Australia Research Council
Funding Acknowledgements
The trial was initially supported by the National Health and Medical Research Council (NHMRC) of Australia (grants 386201, 1041401). Additional funding was received from Chest Heart and Stroke Scotland (Res08/A114), Northern Ireland Chest Heart and Stroke, Singapore Health (SHF/FG401P/2008), the UK Stroke Association (TSA2009/09), and the UK National Institute of Health Research (HTA Project 12/01/16). NHMRC fellowship funding was provided to A.G.T. (1042600), H.D. (336102), and J.B. (1058635). J.B. also received fellowship funding from the Australia Research Council (0991086) and the National Heart Foundation.