Journal article

Risk Factors for Sedation-related Events During Acute Agitation Management in the Emergency Department

Celene YL Yap, David McD Taylor, David CM Kong, Jonathan C Knott, Simone E Taylor, Andis Graudins, Gerben Keijzers, Sanjeewa Kulawickrama, Ogilvie Thom, Luke Lawton, Jeremy Furyk, Daniel P Finucci, Anna Holdgate, Gina Watkins, Peter Jordan, Georgina A Phillips, Jonathan Karro, Esther W Chan, David J Castle

Academic Emergency Medicine | WILEY | Published : 2019

Abstract

OBJECTIVE: The objective was to describe the incidence, nature, and risk factors for adverse events (AEs) among patients who received parenteral sedation for acute agitation in an emergency department (ED) setting. METHODS: We undertook a prospective observational study and a clinical trial of parenteral sedation for the management of acute agitation. We included agitated adult patients who required parenteral sedation from 2014 to 2017 in 12 Australian EDs, excluding those with incomplete information or aged under 18 years. The primary outcome was the number of patients who experienced at least one AE. Multivariable logistic regression was used to determine factors associated with AEs. RESU..

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Grants

Awarded by SHPA Emergency Medicine Grant


Awarded by Emergency Medicine Foundation


Funding Acknowledgements

The study was supported by SHPA Emergency Medicine Grant 2014 (EME 1402); Emergency Medicine Foundation (EMTR-101R23-2015). The funding organizations did not have any role in the design or execution of the study, data analysis, or interpretation.