Journal article

Novel Vitronectin Variations and Their Comparative Analysis in Six Porcine Breeds

Wei Yan, Xutin Zhao, Juyin Li, Long Cheng, Yanqing Li

Animals | MDPI | Published : 2019

Abstract

Vitronectin plays a role in the blood homeostasis and has been implicated in cell adhesion, migration, and proliferation. Vitronectin has a potential role affecting the residual feed intake (RFI) or feeding efficiency in swine production. Its variations have not been reported in Chinese swine breeds. In this study, two regions of porcine vitronectin were analyzed using PCR and sequencing. The sequence analysis revealed thirteen nucleotide substitutions in region 1 (exon 2- exon 3) and three nucleotide substitutions in region 2 (exon 5- intron 5), which would result in five amino acid changes (p.Ala52Thr, p.Leu94Pro, p.Leu94Gln, p.Gln94Pro, and p.Glu126Gly). In region 1, c.156C/T, c.281A/T, a..

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University of Melbourne Researchers

Grants

Awarded by program of capacity building and industrialization of biological breeding from the National Development and Reform Commission


Funding Acknowledgements

This research was funded by the program of capacity building and industrialization of biological breeding from the National Development and Reform Commission, grant number 2150299.