Journal article
Povidone-iodine ear wash and oral cotrimoxazole for chronic suppurative otitis media in Australian aboriginal children: Study protocol for factorial design randomised controlled trial
C Wigger, AJ Leach, J Beissbarth, V Oguoma, R Lennox, S Nelson, H Patel, M Chatfield, K Currie, H Coates, K Edwards, H Smith-Vaughan, K Hare, P Torzillo, S Tong, P Morris
BMC Pharmacology and Toxicology | BMC | Published : 2019
Abstract
Background: Chronic suppurative otitis media (CSOM) is a significant health issue affecting Aboriginal Australians. Long-term hearing loss can cause communication problems, educational disadvantage, and social isolation. Current standard treatment for CSOM in our region is twice daily dry mopping of the pus from the ear canal followed by instillation of ciprofloxacin antibiotic ear drops for up to 16 weeks, or until the discharge resolves for a period of 3 days. The treatment is long, laborious and fails to resolve ear discharge in 70% of cases in remote communities. Bacterial pathogens also persist. Povidone-iodine ear wash is the preferred method of clearing ear discharge in Western Austra..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This study is funded by the National Health and Medical Research Council, NHMRC grant number: 1060764. The funder had no role in the design or conduct of the study, in any future analysis or interpretation of data; or in the preparation of this manuscript. The study sponsor is the Menzies School of Health Research, located in the Northern Territory, Australia.