Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000-17: a spatial and temporal modelling study
Katherine E Battle, Tim CD Lucas, Michele Nguyen, Rosalind E Howes, Anita K Nandi, Katherine A Twohig, Daniel A Pfeffer, Ewan Cameron, Puja C Rao, Daniel Casey, Harry S Gibson, Jennifer A Rozier, Ursula Dalrymple, Suzanne H Keddie, Emma L Collins, Joseph R Harris, Carlos A Guerra, Michael P Thorn, Donal Bisanzio, Nancy Fullman Show all
The Lancet | ELSEVIER SCIENCE INC | Published : 2019
BACKGROUND: Plasmodium vivax exacts a significant toll on health worldwide, yet few efforts to date have quantified the extent and temporal trends of its global distribution. Given the challenges associated with the proper diagnosis and treatment of P vivax, national malaria programmes-particularly those pursuing malaria elimination strategies-require up to date assessments of P vivax endemicity and disease impact. This study presents the first global maps of P vivax clinical burden from 2000 to 2017. METHODS: In this spatial and temporal modelling study, we adjusted routine malariometric surveillance data for known biases and used socioeconomic indicators to generate time series of the clin..View full abstract
Bill & Melinda Gates Foundation and the Wellcome Trust.