Journal article

Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease

Paul Elliott, John C Chambers, Weihua Zhang, Robert Clarke, Jemma C Hopewell, John F Peden, Jeanette Erdmann, Peter Braund, James C Engert, Derrick Bennett, Lachlan Coin, Deborah Ashby, Ioanna Tzoulaki, Ian J Brown, Shahrul Mt-Isa, Mark I McCarthy, Leena Peltonen, Nelson B Freimer, Martin Farrall, Aimo Ruokonen Show all

JAMA | AMER MEDICAL ASSOC | Published : 2009

University of Melbourne Researchers


Awarded by European Union

Awarded by Swiss National Science Foundation

Awarded by British Heart Foundation

Awarded by National Heart, Lung, and Blood Institute

Awarded by European Commission

Awarded by National Institute of Mental Health

Awarded by EC Sixth Framework Programme

Awarded by Medical Research Council

Funding Acknowledgements

The Data from an Epidemiological Study on the Insulin Resistance syndrome (DESIR) received support from INSERM, CNAMTS, Lilly, Novartis Pharma, Sanofi-Aventis, the Association Diabete Risque Vasculaire, the Federation Francaise de Cardiologie, La Fondation de France, ALFEDIAM, ONIVINS, Ardix Medical, Bayer Diagnostics, Becton Dickinson, Cardionics, Merck Sante, Novo Nordisk, Pierre Fabre, Roche, Topcon, and the European Union (P. F.) (Integrated Project EURODIA LSHM-CT-2006-518153 in the Framework Programme 6 [FP06] of the European Community). The Genetic Epidemiology of Metabolic Syndrome (GEMS) study was sponsored in part by GlaxoSmithKline. The German MI Family Study was supported by grants from the Deutsche Forschungsgemeinschaft and the Deutsche Herzstiftung, the National Genome Research Network 2 of the German Federal Ministry of Education and Research, and the Cardiogenics project of the European Union. From the INTERHEART study, Dr Anand holds the Michael G. DeGroot and Heart and Stroke Foundation of Ontario Chair in Population Health and the May Cohen Eli Lilly Endowed Chair in Women's Health Research, McMaster University. The INTERHEART study was funded by the Canadian Institutes of Health Research, the Heart and Stroke Foundation of Ontario, and the International Clinical Epidemiology Network (INCLEN); through unrestricted grants from several pharmaceutical companies (with major contributions from AstraZeneca, Novartis, Sanofi-Aventis, Knoll Pharmaceuticals [now Abbott], Bristol Myers Squibb, and King Pharma); and by various national bodies in different countries as follows: Chile, Universidad de la Frontera, Sociedad Chilena de Cardiologia Filial Sur; Colombia, Colciencias, Ministerio de Salud; Croatia, CroatianMinistry of Science and Technology; Guatemala, Liga Guatemalteca del Corazon; Hungary, Astra Hassle, National Health Science Council, George Gabor Foundation; Iran, Iran Ministry of Health; Italy, Boehringer-Ingelheim; Japan, Sankyo Pharmaceutical Co, Banyu Pharmaceutical Co, Astra Japan; Kuwait, Endowment Fund for Health Development in Kuwait; Pakistan, ATCO Laboratories; Philippines, Philippine Council for Health Research and Development, Pfizer Philippines Foundation, Inc, Astra Pharmaceuticals Inc and the Astra Fund for Clinical Research and Continuing Medical Education, Pharmacia and Upjohn Inc; Poland, Foundation PROCLINICA; Singapore, Singapore National Heart Association; South Africa, Medical Research Council of South Africa, Warner-Parke-Davis Pharmaceuticals, Aventis; Sweden, grant from the Swedish State under the LUA agreement, Swedish Heart and Lung Foundation; Thailand, Heart Association of Thailand, Thailand Research Fund. The International Studies of Infarct Survival (ISIS) trials and epidemiological studies were supported by the manufacturers of the study drugs and by the British Heart Foundation, Medical Research Council, Cancer Research UK, Tobacco Products Research Trust of the UK Department of Health Independent Scientific Committee on Smoking and Health, and Oxford NHS Genetic Knowledge Park. The Lausanne Cohort (CoLaus) study received support from the Giorgi-Cavaglieri Foundation (Toby Johnson, Sven Bergmann), the Universite de Lausanne (Jacques S. Beckmann), and grant 3100AO-116323/1 (Sven Bergmann) from the Swiss National Science Foundation (Murielle Bochud). GlaxoSmithKline provided support to build the CoLaus study (Drs Vollenweider and Waeber). Thiswork was supported by GlaxoSmithKline and the Faculty of Biology and Medicine, Universite de Lausanne, Lausanne, Switzerland.The London Life Siences Population (LOLIPOP) received support from grant SP/04/002 from the British Heart Foundation. The 1966 North Finland Birth Cohort received support from grant 5R01HL087679-02 from the National Heart, Lung, and Blood Institute through the STAMPEED program; the Medical Research Council of the United Kingdom; the European Birth Life-Course Study; contract QLG1-CT2000-01643 from the European Commission "Quality of Life and Management of Living Resources"; the Biocenter Oulu of University of Oulu; the Academy of Finland; and grant 1RL1MH083268-01 from the National Institute of Mental Health. The Precocious Coronary Artery Disease study (PROCARDIS) was funded by the British Heart Foundation, EC Sixth Framework Programme (LSHM33 CT-2007-037273), AstraZeneca AB, and the Knut and Alice Wallenberg Foundation. The Wellcome Trust Case Control Consortium (WTCCC) study received support for recruitment from grants from the British Heart Foundation and the UK Medical Research Council. It also received support from the Wellcome Trust Functional Genomics Initiative in Cardiovascular Genetics. Dr Samani holds a chair funded by the British Heart Foundation.