Journal article

Gene-Targeted Analysis of Copy Number Variants Identifies 3 Novel Associations With Coronary Heart Disease Traits

Sean J Costelloe, Julia S El-Sayed Moustafa, Fotios Drenos, Jutta Palmen, Li Qiao, Stephen Whiting, Michael Thomas, Mika Kivimaki, Meena Kumari, Aroon D Hingorani, Ioanna Tzoulaki, Jaervelin Marjo-Riitta, Ruokonen Aimo, Anna-Liisa Hartikainen, Anneli Pouta, Robin G Walters, Alexandra IF Blakemore, Steve E Humphries, Lachlan JM Coin, Philippa J Talmud

Circulation: Cardiovascular Genetics | LIPPINCOTT WILLIAMS & WILKINS | Published : 2012

University of Melbourne Researchers

Grants

Awarded by British Heart Foundation


Awarded by European Community


Awarded by National Heart, Lung and Blood Institute


Awarded by National Institute on Aging, US, NIH


Awarded by Agency for Health Care Policy Research


Awarded by Academy of Finland


Awarded by University Hospital Oulu, Biocenter, University of Oulu, Finland


Awarded by European Commission


Awarded by NHLBI


Awarded by NIH/NIMH


Awarded by ENGAGE


Awarded by Medical Research Council, UK


Awarded by Wellcome Trust, UK


Awarded by MRC


Awarded by Wellcome Trust


Awarded by Diabetes UK


Awarded by Medical Research Council


Funding Acknowledgements

Drs Hingorani, Humphries, and P.J. Talmud were funded by the British Heart Foundation under RG08/014, and Dr Kumari was funded by the British Heart Foundation under PG07/133/24260. J.S.E-S. Moustafa was funded by an Imperial College Division of Medicine PhD studentship. Drs Coin and Li received funding from European Community's Seventh Framework Programme (grant No. 223367, MultiMod). Drs Kivimaki and Kumari were partially supported by the National Heart, Lung and Blood Institute (NHLBI: HL36310). The WHII study was supported by grants from the Medical Research Council; British Heart Foundation; Health and Safety Executive; Department of Health; National Heart, Lung and Blood Institute (NHLBI: HL36310), and National Institute on Aging (AG13196), US, NIH; Agency for Health Care Policy Research (HS06516); and the John D and Catherine T MacArthur Foundation Research Networks on Successful Midlife Development and Socioeconomic Status and Health. NFBC1966 received financial support from the Academy of Finland (project grants 104781, 120315, 129269, 1114194, 139900/24300796, Center of Excellence in Complex Disease Genetics and SALVE), University Hospital Oulu, Biocenter, University of Oulu, Finland (75617), the European Commission (EURO-BLCS, Framework 5 award QLG1-CT-2000-01643), NHLBI grant 5R01HL087679-02 through the STAMPEED program (1RL1MH083268-01), NIH/NIMH (5R01MH63706:02), ENGAGE project and grant agreement HEALTH-F4-2007-201413, the Medical Research Council, UK (G0500539, G0600705, G0600331, PrevMetSyn/SALVE, PS0476), and the Wellcome Trust (project grant GR069224, WT089549), UK. Replication genotyping was supported, in part, by MRC grant G0601261, Wellcome Trust grants 085301, 090532, and 083270, and Diabetes UK grants RD08/0003704 and BDA 08/0003775. The DNA extractions, sample quality controls, biobank upkeeping, and aliquoting were performed in the National Public Health Institute, Biomedicum Helsinki, Finland, and were supported financially by the Academy of Finland and Biocentrum Helsinki. Genotyping of the FCC groups had previously been funded by Genome Canada and Genome Quebec.