Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study

F Martinón-Torres; A Salas; I Rivero-Calle; M Cebey-López; J Pardo-Seco; JA Herberg; NP Boeddha; DS Klobassa; F Secka; S Paulus; R de Groot; LJ Schlapbach; GJ Driessen; ST Anderson; M Emonts; W Zenz; ED Carrol; M Van der Flier; M Levin; L Coin; S Gormley; S Hamilton; B Hourmat; C Hoggart; M Kaforou; V Sancho-Shimizu; V Wright; A Abdulla; P Agapow; M Bartlett; E Bellos; H Eleftherohorinou; R Galassini; D Inwald; M Mashbat; S Menikou; S Mustafa; S Nadel; R Rahman; C Thakker; S Bokhandi; S Power; H Barham; N Pathan; J Ridout; D White; S Thurston; S Faust; S Patel; J McCorkell; P Davies; L Crate; H Navarra; S Carter; R Ramaiah; R Patel; C Tuffrey; A Gribbin; S McCready; M Peters; K Hardy; F Standing; L O'Neill; E Abelake; A Deep; E Nsirim; A Pollard; L Willis; Z Young; C Royad; S White; PM Fortune; P Hudnott; A Salas Ellacuriaga; F Álvez González; R Barral-Arca; MJ Curras-Tuala; N García; L García Vicente; A Gómez-Carballa; J Gómez Rial; A Grela Beiroa; A Justicia Grande; P Leboráns Iglesias; AE Martínez Santos; N Martinón-Torres; JM Martinón Sánchez; B Morillo Gutiérrez; B Mosquera Pérez; P Obando Pacheco; S Pischedda; C Rodríguez-Tenreiro; L Redondo-Collazo; S Serén Fernández; MDS Porto Silva; A Vega; L Vilanova Trillo; SB Reyes; MC León León; Á Navarro Mingorance

Journal article

Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study

F Martinón-Torres, A Salas, I Rivero-Calle, M Cebey-López, J Pardo-Seco, JA Herberg, NP Boeddha, DS Klobassa, F Secka, S Paulus, R de Groot, LJ Schlapbach, GJ Driessen, ST Anderson, M Emonts, W Zenz, ED Carrol, M Van der Flier, M Levin, L Coin Show all

Lancet Child and Adolescent Health | ELSEVIER SCI LTD | Published : 2018

DOI: 10.1016/S2352-4642(18)30113-5

Abstract

Background: Sepsis and severe focal infections represent a substantial disease burden in children admitted to hospital. We aimed to understand the burden of disease and outcomes in children with life-threatening bacterial infections in Europe. Methods: The European Union Childhood Life-threatening Infectious Disease Study (EUCLIDS) was a prospective, multicentre, cohort study done in six countries in Europe. Patients aged 1 month to 18 years with sepsis (or suspected sepsis) or severe focal infections, admitted to 98 participating hospitals in the UK, Austria, Germany, Lithuania, Spain, and the Netherlands were prospectively recruited between July 1, 2012, and Dec 31, 2015. To assess disease..

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