Journal article
Dental pulp stem cells therapy overcome photoreceptor cell death and protects the retina in a rat model of sodium iodate-induced retinal degeneration
HA Alsaeedi, AEH Koh, C Lam, MBA Rashid, MHN Harun, MFBM Saleh, SW Teh, CD Luu, MH Ng, HM Isa, SN Leow, KY Then, MLC Bastion, PL Mok, BS Muthuvenkatachalam, AV Samrot, KB Swamy, J Nandakumar, SS Kumar
Journal of Photochemistry and Photobiology B Biology | ELSEVIER SCIENCE SA | Published : 2019
Abstract
Blindness and vision loss contribute to irreversible retinal degeneration, and cellular therapy for retinal cell replacement has the potential to treat individuals who have lost light sensitive photoreceptors in the retina. Retinal cells are well characterized in function, and are a subject of interest in cellular replacement therapy of photoreceptors and the retinal pigment epithelium. However, retinal cell transplantation is limited by various factors, including the choice of potential stem cell source that can show variability in plasticity as well as host tissue integration. Dental pulp is one such source that contains an abundance of stem cells. In this study we used dental pulp-derived..
View full abstractGrants
Awarded by Institute of Postgraduate Studies, Universiti Sains Malaysia
Funding Acknowledgements
This research was supported by the Research and Management Centre of Universiti Putra Malaysia through the Putra Graduate Initiative (IPS) grant (Grant No.: 9544300) and Geran Putra Berimpak (Grant No.: 9674600).