Journal article

Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis

Bradley L Hoare, Martina Kocan, Shoni Bruell, Daniel J Scott, Ross AD Bathgate

Pharmacology Research and Perspectives | JOHN WILEY & SONS LTD | Published : 2019

DOI: 10.1002/prp2.513

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Related Projects (1)

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UNRAVELLING THE BINDING AND ACTIVATION MECHANISM OF A COMPLEX G PROTEIN-COUPLED RECEPTOR

The peptide hormone relaxin is currently in a Phase III trial for the treatment of heart failure. However the peptide is not a good drug as ..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

National Health and Medical Research Council, Grant/Award Number: 1100676 and 1135837; Victorian Government Operational Infrastructure Support Program

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Keywords

Relaxin
Life Sciences & Biomedicine
Protein-Coupled Receptors
Resonance Energy-Transfer
Bioluminescence Resonance Energy Transfer Techniques
Protein Multimerization
Rxfp1
Bioluminescence Resonance Energy Transfer
Receptors, G-Protein-Coupled
G Protein‐coupled Receptor
Hibit
Luciferases
G Protein-Coupled Receptor
Hek293 Cells
Heterodimerization
Binding Site
Luciferase
Splice Variants
Staining and Labeling
Oligomerization
Science & Technology
H2 Relaxin
Nanoluc
Homodimerization
Pharmacology & Pharmacy
Humans
Receptors, Peptide