Environmental enrichment reduces the propensity to relapse following punishment-imposed abstinence of alcohol seeking
Erin J Campbell, Shubo Jin, Andrew J Lawrence
Physiology & Behavior | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2019
Environmental enrichment during periods of abstinence can reduce the risk of relapse to drug-seeking behavior. We trained rats to self-administer alcohol in one environment (Context A), then punished their alcohol-reinforced lever responses in a different environment using contingent foot shock (Context B). Rats were then kept in forced abstinence in either standard housing or environmental enrichment conditions for 31 days. The following day, we examined alcohol seeking behavior. We found a significant reduction in alcohol seeking behavior in Context A after environmental enrichment. Our results suggest that environmental enrichment can reduce alcohol seeking behavior following a period of ..View full abstract
Related Projects (1)
Awarded by National Health and Medical Research Council
This work was supported by a National Health and Medical Research Council Project Grant (1105741). AJL is a NHMRC Principal Fellow (1116930) and EJC is supported by the Jack Brockhoff Early Career Researcher Grant Scheme. We acknowledge the Victorian State Government Operational Infrastructure Scheme.