Journal article

Cognitive consequences of coexisting temporal lobe developmental malformations and hippocampal sclerosis

R Martin, R Dowler, S Ho, F Gilliam, E Faught, R Morawetz, R Kuzniecky

NEUROLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 1999

Abstract

OBJECTIVE: To characterize patterns of cognitive functioning in a well-defined group of patients with MRI-identified coexisting left temporal lobe developmental malformations (TLDM) and mesial temporal sclerosis (MTS), and to examine neuropsychological outcome in this dual-pathology group following epilepsy surgery. METHODS: Cognitive functioning in patients with left TLDM and MTS (n = 15) was compared with patients with isolated left MTS (n = 40). TLDM and MTS were identified by high-quality MRI protocol. Patients were administered a battery of neuropsychology tests as part of their presurgical workup for possible epilepsy surgery. Unilateral temporal lobe resection was performed on 10 of t..

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