Development of a multicentre automated model to reduce planning variability in radiotherapy of prostate cancer
Vanessa Panettieri, David Ball, Adam Chapman, Nigel Cristofaro, Janet Gawthrop, Peter Griffin, Sisira Herath, Susan Hoyle, Liam Jukes, Tomas Kron, Cathy Markham, Loretta Marr, Phillip Moloney, Flavio Nelli, Prabhakar Ramachandran, Amanda Smith, Colin J Hornby
PHYSICS & IMAGING IN RADIATION ONCOLOGY | ELSEVIER | Published : 2019
Background and purpose: Inter-institutional studies highlighted correlation between consistent radiotherapy quality and improved overall patient survival. In treatment planning automation has the potential to address differences due to user-experience and training, promoting standardisation. The aim of this study was to evaluate implementation and clinical effect of a multicentre collaboratively-developed automated planning model for Intensity-Modulated Radiation Therapy/Volumetric-Modulated Arc Therapy of prostate. The model was built using a variety of public institutions' clinical plans, incorporating different contouring and dose protocols, aiming at minimising their variation. Methods a..View full abstract
The authors would like to acknowledge the Department of Health and Human Services of the State of Victoria, Australia, for the support provided in this project.