Understanding the interactions between iron supplementation, infectious disease and adverse birth outcomes is essential to guide public health recommendations
Freya JI Fowkes, Eliza Davidson, Paul A Agius, James G Beeson
BMC MEDICINE | BMC | Published : 2019
Pregnant women are highly susceptible to anaemia and iron deficiency due to the increased demands of pregnancy as well as other factors. Iron supplementation is recommended in pregnancy, yet the benefits on newborn outcomes are variable between populations, most likely due to the heterogeneity in the prevalence of iron deficiency, detrimental birth outcomes and infectious diseases. Furthermore, there are concerns regarding iron supplementation in malaria-endemic areas due to reports of increased risk of malaria in those receiving iron. This is compounded by limited knowledge of how iron deficiency, anaemia, malaria, and other infections may interact to influence birth outcomes. In a recent c..View full abstract
FJIF and JGB are funded by the Australian National Health and Medical Research Council (NHMRC), and ED is supported by an Australian Postgraduate Award.