Self-collected compared with professional-collected swabbing in the diagnosis of influenza in symptomatic individuals: A meta-analysis and assessment of validity
Christopher P Seaman, Thi Tuyet Tran Luong, Benjamin J Cowling, Sheena G Sullivan
JOURNAL OF CLINICAL VIROLOGY | ELSEVIER | Published : 2019
Self-collected nasal swabs offer a cheaper alternative to professional-collected swabs for influenza testing. However, the diagnostic accuracy of self-collection has not been quantitatively reviewed. We identified 14 studies that compared diagnostic accuracy of self-collected to professional-collected swabs in influenza symptomatic individuals. Self-collected swabs were found to be highly acceptable, simple and comfortable to use. Data from nine studies were meta-analyzed. Pooled sensitivity was 87% (95% CI: 80%, 92%) and specificity was 99% (95% CI: 98%, 100%), compared to professional-collected swabs in the diagnosis of influenza. Pooled sensitivity and specificity estimates were used to a..View full abstract
The WHO Collaborating Centre for Reference and Research on Influenza is supported by the Australian Government Department of Health. LTTT received an Australian Awards Scholarship, and acknowledges the support of the Australian Government.