Journal article
Antibiotic prophylaxis in the surgical management of miscarriage in low-income countries: a cost-effectiveness analysis of the AIMS trial
I Goranitis, DM Lissauer, A Coomarasamy, A Wilson, J Daniels, L Middleton, J Bishop, CA Hewitt, AD Weeks, C Mhango, R Mataya, I Ahmed, OT Oladapo, J Zamora, TE Roberts
Lancet Global Health | ELSEVIER SCI LTD | Published : 2019
Abstract
Background: There is ongoing debate on the clinical benefits of antibiotic prophylaxis for reducing pelvic infection after miscarriage surgery. We aimed to study the cost-effectiveness of antibiotic prophylaxis in the surgical management of miscarriage in low-income countries. Methods: We did an incremental cost-effectiveness analysis using data from 3412 women recruited to the AIMS trial, a randomised, double-blind, placebo-controlled trial designed to evaluate the effectiveness of antibiotic prophylaxis in the surgical management of miscarriage in Malawi, Pakistan, Tanzania, and Uganda. Economic evaluation was done from a health-care-provider perspective on the basis of the outcome of cost..
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Awarded by Center for Global Health
Funding Acknowledgements
The study was funded by the UK Medical Research Council, the Wellcome Trust, and the UK Department for International Development, as part of the Joint Global Health Trials Scheme.