Trajectories of body mass index in adulthood and all-cause and cause-specific mortality in the Melbourne Collaborative Cohort Study
Yi Yang, Pierre-Antoine Dugue, Brigid M Lynch, Allison M Hodge, Amalia Karahalios, Robert J MacInnis, Roger L Milne, Graham G Giles, Dallas R English
BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2019
OBJECTIVE: Limited research has assessed the association between patterns of body mass index (BMI) change across adulthood and mortality. We aimed to identify groups of individuals who followed specific group-based BMI trajectories across adulthood, using weight collected on three occasions and recalled data from early adulthood, and to examine associations with all-cause and cause-specific mortality. DESIGN: Prospective cohort study. SETTING: Melbourne, Australia. PARTICIPANTS: Adults (n=29 881) enrolled in the Melbourne Collaborative Cohort Study, who were aged from 40 to 70 years between 1990 and 1994, and had BMI data for at least three time points. OUTCOME: Deaths from any cause before ..View full abstract
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Awarded by National Breast Cancer Foundation
YY is supported by a Melbourne Research Scholarship from the University of Melbourne. BML is supported by a fellowship from the National Breast Cancer Foundation (ECF-15-012).