Journal article
Multidimensional evaluation of changes in limb function following botulinum toxin injection in persons with stroke
B Amatya, LE Cofré Lizama, A Elmalik, A Bastani, MP Galea, F Khan
Neurorehabilitation | IOS PRESS | Published : 2019
DOI: 10.3233/NRE-192722
Abstract
BACKGROUND: There are limited evidence of instrumented measures of gait and balance to determine the functional effects of botulinum toxin injections (BoNT-A) in spasticity after stroke. OBJECTIVE: To evaluate the functional changes in gait and balance following upper limb and lower limb BoNT-A in persons with stroke. METHODS: A pre-post prospective study of 35 stroke patients with upper and/or lower limb spasticity after focal treatment with BoNT-A. Assessments were at baseline (T0), 6-weeks (T1) and 12-weeks (T2), using validated subjective and objective physical activity measures. RESULTS: After BoNT-A injections, significant improvements in most measures of impairments, activity and part..
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Funding Acknowledgements
No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the authors or upon any organisation with which the authors are associated. This study was supported by an educational grant from Merz Australia Pty Ltd to the Royal Melbourne Hospital Foundation.