Journal article

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Claire Vennin, Pauline Melenec, Romain Rouet, Max Nobis, Aurelie S Cazet, Kendelle J Murphy, David Herrmann, Daniel A Reed, Morghan C Lucas, Sean C Warren, Zehra Elgundi, Mark Pinese, Gabriella Kalna, Daniel Roden, Monisha Samuel, Anaiis Zaratzian, Shane T Grey, Andrew Da Silva, Wilfred Leung, Suresh Mathivanan Show all

Nature Communications | NATURE PUBLISHING GROUP | Published : 2019


Awarded by United States NIH

Funding Acknowledgements

The authors wish to thank Brooke Pereira, Shona Ritchie and Cecilia Chambers for critical reading of the manuscript. This work was supported by NHMRC, Cancer Council NSW, Cancer Institute NSW (M.N., D.H., and T.R.C), Len Ainsworth Pancreatic Cancer Fellowship (P.T.) and Philip Hemstritch Pancreatic Cancer Fellowship (M.P.), Royal Australasian College of Physicians Research Foundation scholarships, a CRUK core grant, an NBCF fellowship (D.R.). This project was made possible by an Avner Pancreatic Cancer Foundation Grant. P.T. is a recipient of an NHMRC Senior Research Fellowship, C.V. is a recipient of a post-doctoral HFSP fellowship, T.R.C. is a recipient of an NHMRC RD Wright Biomedical Career Development Fellowship, A.W.B. was supported by the Royal Society of NZ James Cook Fellowship and Health Research Council of NZ research grants. Y.W. was supported by a United States NIH CA204704 and CA209629. B.L.P. is a recipient of an NHMRC Early Career Fellowship.