Journal article

Point-of-care testing and treatment of sexually transmitted infections to improve birth outcomes in high-burden, low-income settings: Study protocol for a cluster randomized crossover trial (the WANTAIM Trial, Papua New Guinea)

Andrew Vallely, William Pomat, Caroline Homer, Rebecca Guy, Stanley Luchters, Glen Mola, Grace Kariwiga, Lisa Vallely, Virginia Wiseman, Chris Morgan, Handan Wand, Stephen Rogerson, Sepehr Tabrizi, David Whiley, Nicola Low, Rosanna Peeling, Peter Siba, Michaela Riddell, Moses Laman, John Bolnga Show all

Wellcome Open Research | Published : 2019

Abstract

Background: Chlamydia trachomatis , Neisseria gonorrhoeae , Trichomonas vaginalis and bacterial vaginosis have been associated with preterm birth and low birth weight, and are highly prevalent among pregnant women in many low- and middle-income settings. There is conflicting evidence on the potential benefits of screening and treating these infections in pregnancy. Newly available diagnostic technologies make it possible, for the first time, to conduct definitive field trials to fill this knowledge gap. The primary aim of this study is to evaluate whether antenatal point-of-care testing and immediate treatment of these curable sexually transmitted and genital infections (STIs) leads to reduc..

View full abstract