Journal article

Changes in heart rate and blood pressure during nocturnal hot flashes associated with and without awakenings

Fiona C Baker, Mohamad Forouzanfar, Aimee Goldstone, Stephanie A Claudatos, Harold Javitz, John Trinder, Massimiliano de Zambotti

Sleep | OXFORD UNIV PRESS INC | Published : 2019


Hot flashes (HFs) are a hallmark of menopause in midlife women. They are beyond bothersome symptoms, having a profound impact on quality of life and wellbeing, and are a potential marker of cardiovascular (CV) disease risk. Here, we investigated the impact on CV functioning of single nocturnal HFs, considering whether or not they were accompanied by arousals or awakenings. We investigated changes in heart rate (HR, 542 HFs), blood pressure (BP, 261 HFs), and pre-ejection period (PEP, 168 HFs) across individual nocturnal physiological HF events in women in the menopausal transition or post-menopause (age: 50.7 ± 3.6 years) (n = 86 for HR, 45 for BP, 27 for PEP). HFs associated with arousals/a..

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Awarded by National Institutes of Health

Funding Acknowledgements

The study is supported by the National Institutes of Health (HL103688, F.C.B.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.