Journal article

A systematic review of the cost-effectiveness of uterotonic agents for the prevention of postpartum hemorrhage

Theresa A Lawrie, Ewelina Rogozinska, Pauline Sobiesuo, Joshua P Vogel, Laura Ternent, Olufemi T Oladapo

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | WILEY | Published : 2019

Abstract

BACKGROUND: Several uterotonic options exist for prevention of postpartum hemorrhage (PPH); hence, cost-effectiveness is an important decision-making criterion affecting uterotonic choice. OBJECTIVE: To conduct a systematic review of cost-effectiveness of uterotonics for PPH prevention to support a WHO guideline update. SEARCH STRATEGY: We searched major databases from 1980 to June 2018 and the National Health Services Economic Evaluation (NHS EED) database from inception (1995) to March 2015 for eligible studies. SELECTION CRITERIA: We included comparative economic evaluations, cost-utility analyses, and resource-utilization studies. DATA COLLECTION AND ANALYSIS: Two reviewers independently..

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