Journal article

Modeling Progress Toward Elimination of Hepatitis B in Australia

Karen McCulloch, Nicole Romero, Jennifer MacLachlan, Nicole Allard, Benjamin Cowie

HEPATOLOGY | WILEY | Published : 2020

Abstract

BACKGROUND AND AIMS: Chronic hepatitis B (CHB) is a significant global health concern, and the most prevalent blood-borne virus in Australia. World Health Organization (WHO) member states have committed to global elimination, with targets to diagnose 90% of people living with CHB, treat 80% of those eligible, and reduce attributable deaths by 65% by the year 2030. Australia has committed to national targets of 80% diagnosed, 20% on treatment, and a 30% reduction in deaths by 2022. APPROACH AND RESULTS: We constructed and implemented a mathematical model to estimate the burden of CHB incorporating vaccination, phases of infection, cirrhosis progression, and mortality attributed to decompensat..

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Grants

Awarded by Blood Borne Viruses and Sexually Transmissible Infections Surveillance and Research Programme-Surveillance for Hepatitis B Indicators, Australian Department of Health


Funding Acknowledgements

Supported by the Blood Borne Viruses and Sexually Transmissible Infections Surveillance and Research Programme-Surveillance for Hepatitis B Indicators (H1516G021), Australian Department of Health. While the Australian Department of Health provides financial support for this project, the material contained, or the views expressed in this resource, should not be taken to represent the views of the Australian Department of Health.