International comparison of cosmetic outcomes of breast conserving surgery and radiation therapy for women with ductal carcinoma in situ of the breast
Ivo A Olivotto, Emma Link, Claire Phillips, Timothy J Whelan, Guy Bryant, Ian H Kunkler, A Helen Westenberg, Kash Purohit, Verity Ahern, Peter H Graham, Mohamed Akra, Orla McArdle, Joanna J Ludbrook, Jennifer A Harvey, John H Maduro, Carine Kirkove, Guenther Gruber, Joseph D Martin, Ian D Campbell, Geoff P Delaney Show all
Radiotherapy and Oncology | ELSEVIER IRELAND LTD | Published : 2020
PURPOSE: To assess the cosmetic impact of breast conserving surgery (BCS), whole breast irradiation (WBI) fractionation and tumour bed boost (TBB) use in a phase III trial for women with ductal carcinoma in situ (DCIS) of the breast. MATERIALS AND METHODS: Baseline and 3-year cosmesis were assessed using the European Organization for Research and Treatment of Cancer (EORTC) Cosmetic Rating System and digital images in a randomised trial of non-low risk DCIS treated with postoperative WBI +/- TBB. Baseline cosmesis was assessed for four geographic clusters of treating centres. Cosmetic failure was a global score of fair or poor. Cosmetic deterioration was a score change from excellent or good..View full abstract
Supported in part by grants or research support from the National Health and Medical Research Council of Australia, Susan G. Komen for the Cure (R), Breast Cancer Now, the OncoSuisse Swiss Federation Against Cancer, the Dutch Cancer Society and the Canadian Cancer Society through the Canadian Cancer Trials Group.